Recently, researchers at the Moscow State Medical College have developed new and effective methods to diagnose and treat cervical dysplasia. The new method has been proven effective for all patients participating in the study. The treatment of cervical cancer is an urgent issue in gynecological oncology, because current diagnostic methods include surgical intervention. Researchers pointed out that in some cases, collecting tissue samples for biopsy may cause undesirable phenomena and lead to dangerous consequences such as uterine bleeding.
In this regard, researchers from the Moscow State Medical School have proposed a fluorescent diagnostic method that can obtain information about the condition of the tissue without affecting the biological processes that occur in the tissue. In fluorescence diagnosis and photodynamic therapy, photosensitizers (photosensitive substances) are introduced into human blood. Tumor cells are more likely to accumulate these substances in large amounts than healthy cells. After a period of time, most photosensitizers will leave normal cells but remain in cancer cells. Chlorine-type photosensitizers absorb radiation, produce reactive oxygen species, destroy nearby cancer cells and destroy blood vessels, thereby preventing cancer cells from absorbing essential nutrients. Polina Alekseeva, a graduate student at RNUMEPhI's Institute of Laser Plasma Technology, said: This method can pinpoint the boundaries of the tumor. She also has cervical tumors. Someone pointed out that the use of spectral fluorescence for diagnosis can control all stages of the photodynamic therapy process.
The results of clinical studies conducted by scientists and surgeons show that morphologically confirmed leukoplakia results indicate that photodynamic therapy has been successfully used in all patients with epithelial thickening and keratinization and cervical dysplasia (precancerous state). Photodynamic therapy Also got a successful treatment. After 3 months, all patients recorded complete regression of the pathologically changed tissue (no tumor cells). The results of the study are also particularly important for women planning to become pregnant. We have confirmed the possibility of using new methods to destroy human papillomavirus while maintaining the normal physiological structure of the cervix
In the future, the NRNUMEPhI research team has already performed photodynamic processing on it. I hope to improve my method and change the treatment strategy in time to avoid recurrence caused by underexposure or overexposure.