Tdap疫苗,霍帕氏咳嗽疫苗 z-bo 2020-10-09 285

　　Dr. Elyse O. Kharbanda of the Minneapolis Institute of Health Peer Education in the United States published an observational study in the Journal of the American Medical Association (JAMA) on November 11, Hopper's Cough Vaccine (Tdap) vaccine Will not increase the risk of high blood pressure, premature delivery or age of pregnancy (SGA) in pregnant women.

　　Due to the recent cough outbreak, the Immunization Practice Advisory Committee of the Centers for Disease Control and Prevention recommends that all pregnant women receive the Tdap vaccine. The best time to suck blood is 27-36 weeks of pregnancy. Yes. However, according to Dr. Elyse O. Kharbanda and colleagues of the Minneapolis Health Partnership Education Institute, the data on the potential adverse effects of vaccines on mothers and children are "limited." To test this question, the researchers analyzed the birth information of 123,494 pregnant women who got pregnant at two vaccination facilities in California in three years in the vaccine safety database. During pregnancy, a total of 26,229 (21%) pregnant women received the Tdap vaccine, while 97,265 pregnant women were not immunized. 46% of pregnant women received Tdap before pregnancy.

　　Dr. Karbanda and colleagues report that preterm birth rates for vaccinated and unvaccinated pregnant women are 6.3% and 7.8%, respectively. There was no statistical difference between the two groups. At the same time, the incidence of SGA was roughly the same between the two groups. They are 8.4% and 8.3% respectively. The incidence of hypertension in pregnant women (including hypertension during pregnancy, hypertension during pregnancy, antenatal disease and childhood without special instructions) did not differ significantly, being 8.2% and 8.0%, respectively. The researchers found that this weak correlation is a residual entanglement factor, especially because the analysis data cannot regulate the inflammation of choroidal sheep, and the inflammation of choroidal sheep is an important risk factor for prolonging membrane rupture time, prolonging working time and delivery. Point out that it may be caused by. Pathogens of the birth canal.

　　This study was sponsored by the Centers for Disease Control and Prevention (CDC). Dr. Halbanda said that there is no financial conflict of interest. Some of her colleagues have reported conflicts of interest with GlaxoSmithKline, Sanofi Pasteur, Pfizer, Merck, Novartis, Nuron Biotech, ProteinScience and MedImmune. The two researchers are CDC employees.