金葡菌毒素,组织再生 z-bo 2020-10-16 276

　　Millions of Staphylococcus aureus bacteria are found on the skin and upper respiratory mucosa of a quarter of people. However, in some cases, harmless bacteria can become pathogens, causing skin irritation, lung infections, and even sepsis in the worst case. Professor Oliva Werz of Friedrichschiller University in Jena, Germany, said: “This is especially true when bacteria grow too fast, for example when a person’s immune system is infected or weakened by injury. Time.

　　The author studied the molecular defense mechanism of the human immune system against Staphylococcus aureus infection. A surprising discovery was made, and the relevant results were published in the recent "Celleports" magazine. This study found that Staphylococcus aureus can damage cells and tissues. Toxic mixtures also have a positive effect: bacterial toxins stimulate specific immune cells to produce special messenger substances, thereby reducing inflammation and promoting tissue healing. Professor Wertz hopes that this previously unknown mechanism will help treat skin inflammation and chronic wounds in the future.

　　In the latest study, researchers from the Fritz Lipman Institute (FLI), together with colleagues from Harvard Medical School and the University of Naples, specifically studied the bacterial toxin research "α-hemoglobin." "The effect on M2 macrophages. M2 macrophages are immune cells. In the later stages of the inflammatory response, they can reliably kill dead bacteria and damaged cellular components and ensure tissue regeneration.

　　Researchers Alphahemolicin binds to specific receptor proteins on the surface of M2 macrophages, resulting in the production of anti-inflammatory messenger substances in the cells and calming inflammation. In this study, scientists found these mediators and we also proved that it can promote animal models.