关节损伤 z-bo 2020-10-16 760

　　Anterior cruciate ligament (ACL) injury can lead to severe osteoarthritis. Currently, new interdisciplinary research shows that the accumulation of proteins used to smooth joints may actually be a precursor to joint disease. This article was recently published in "Celleports" magazine. This is the first paper to study the role of a protein called lubricin in canine ACL-type injuries. It can also have a significant impact on similar personal injuries and treatment and therapeutic potential.

　　Dr. Heidi Sink said: “Oil is essential for normal joint function and cartilage lubrication. If animals cannot make this protein, then destructive joints will affect all major weight-bearing joints. It develops into disease. I know.” About Red There are conflicting data on the role of mycin in joint damage, but this phenomenon is common in mammals, including humans. According to a study by Reesink, dogs with torn knee ligaments have an increased joint lubrication coefficient. This is contrary to the assumption of traditional medicine. Eesink said: "In this regard, the previous central idea was that Lublin helps reduce joint disease." Among the three dogs with joint injuries, Lublin suffered from arthritis at the first injury. Where. No sign, but X-ray. Last time it increased significantly. Eesink said: "This shows that the increased oil may actually be a biomarker for predicting future osteoarthritis. After months to years of ACL damage, the oil will increase significantly. The increase in lubricin may also be joint. This It shows that the instability is still going on." Eesink said that the increase in lubricin was caused by clinicians. statement. He said this may be a signal to intervene or try other treatments. Injuries to the anterior cruciate ligament (ACL) can cause severe osteoarthritis. Currently, new interdisciplinary research shows that the accumulation of proteins used to smooth joints may actually be a precursor to joint disease.

　　This article was recently published in the journal Cell Reports. This is the first paper to study the role of a protein called lubricin in canine ACL-type injuries. It can also have a significant impact on similar personal injuries and treatment and therapeutic potential.

　　Dr. Heidi Sink said: “Oil is essential for normal joint function and cartilage lubrication. If animals cannot make this protein, they will develop into destructive joint diseases that affect all major weight-bearing joints.”

　　There are conflicting data on the role of Lubricin in joint damage, which is common in mammals including humans. Reesink's research shows that the lubrication coefficient of dog joints with torn knee ligaments is contrary to traditional medical assumptions. Eesink said: "In this regard, the previous central idea was that wind protein helps reduce joint disease."

　　Among the three dogs with joint injuries, Lublin suffered from arthritis at the first injury. No sign, but X-ray. Last time it increased significantly.

　　Eesink said: "This shows that the increased oil may actually be a predictive biomarker of osteoarthritis in the future. After months to years of ACL damage, the oil will increase significantly. There is also an increase in lubricin, which may be combined. This Indicates continued instability."

　　Esink said that the increase in lubrication was caused by clinicians. He said this may be a signal to intervene or try other treatments.