癌干细胞 z-bo 2020-10-20 268

　　Japanese researchers have discovered that fluorescent reagents can bind to cancer stem cells, which not only makes cancer stem cells glow, but also has the effect of inhibiting cancer stem cells. This discovery helps to promote the development of new methods of treating cancer. Cancer stem cells are cancer cells with the characteristics of stem cells, which have the characteristics of "self-renewal" and "multicellular differentiation". It is believed that such cells can form tumors and even develop into cancer. Current cancer treatment is mainly to kill cancer cells through drugs and radiation therapy. However, if the cancer cell stem cells remain, the cancer cells will proliferate again. Several agents for inhibiting cancer stem cells have been discovered, but the technology to completely kill cancer stem cells has not made much progress, and the process of cancer stem cell apoptosis is still unclear.

　　Benmy University researchers raised clear zebrafish, transplanted human cancer stem cells into it, and injected hundreds of fluorescent reagents for testing. Finally, a fluorescent reagent called "DiOC5(3)" enables the light of cancer stem cells not only to clearly see the concentration of cancer stem cells, but also to prevent the growth of cancer stem cells. Cancer stem cells that emit light when used in combination with the reagent will not emit light after apoptosis, so the location and number of cancer stem cells remaining in the body can be determined.