动物实验,修复大脑 z-bo 2020-10-21 304

　　Recently, Canadian researchers discovered that running can cause the production of molecules that can repair certain brain damage in animal models. This molecule, called VGF nerve growth factor, can cure the "protective layer" that wraps and isolates nerve fibers. The research report was published on "Cell-Communication". These results may pave the way for research on new therapies for specific neurodegenerative diseases.

　　David J, corresponding author and senior scientist at Otawa Hospital and Otawa University. Pickets said: "Obviously, VGF plays an important role in healing damaged areas of the brain. Further research is needed to determine whether it can help treat multiple sclerosis and other neurodegenerative diseases."

　　Researchers created a mouse model of a particularly small brain. The brain is an important area of the brain responsible for balance and coordination. These defective mice have difficulty maintaining balance and have a short life span of only 25-40 days. After that, they fixed the wheels on some mouse cages for operation. Surprisingly, mice that have the opportunity to run live longer than 12 months (this is the relatively normal lifespan of mice). Compared with less active mice, in addition to prolonging their lifespan, running mice can also gain weight and have a stronger sense of balance. However, if the runner is removed, the symptoms will reappear and the life span will be shortened. Researchers are studying

　　The brains of mice found that the amount of nerve myelin in the brains of running mice increased. Myerin is a white grease that acts like an insulating layer on a cable. Without it, neurons will not be able to send information quickly and efficiently.

　　Through careful study, the researchers found that VGF played a role here. It has antidepressant effects and can make exercise more enjoyable. They used this virus to introduce the VGF protein into the blood of non-stray mice. As a result, the mice reacted like running, with more isolation of damaged areas of the brain and fewer disease symptoms.