帕金森病 z-bo 2020-10-26 364

　　The detection of caffeine levels in the blood may be a simple diagnostic method for Parkinson's disease. According to a new study published in the third issue of the American Journal of Neurology, even if people consume as much caffeine as normal people, the blood levels of caffeine in Parkinson's disease patients are still higher than the general population. It is much lower.

　　Caffeine is a central nervous system stimulating component of tea and coffee. Considering that previous studies have shown that caffeine can reduce the risk of Parkinson's disease, researchers at Juntendo University in Japan tested 108 Parkinson's disease patients with an average medical history of 6 years and 31 healthy peers. After the human body metabolizes caffeine, the level of caffeine and 11 by-products in the blood. The results showed that when the subjects’ caffeine intake was equivalent to two cups of coffee per day, the blood caffeine level of the Parkinson’s patient group was 2.4 picomoles per milliliter, while the blood caffeine level of the normal group was 1 milliliter. The results showed that it was 7.9 picomoles per liter. Moore; In the blood of Parkinson's disease patients, the levels of 9 of the 11 byproducts of caffeine metabolism are significantly reduced. Researchers also tested genes related to mutations in participants and caffeine metabolism and found that Parkinson's disease patients are no different from the general public in this respect. Researchers believe that the caffeine level test in the blood can be used to reliably diagnose Parkinson's disease. If a score of 1 means that all patients have been diagnosed, the score for this test is 0.98. David Mu of the University of Toronto, Canada? Professor Oz wrote a review article for this study. He also pointed out that the study also showed that blood caffeine levels in patients with advanced Parkinson's disease are not low. This means that this reduction occurs in the early stages of Parkinson's disease.

　　"If these results are confirmed, they may indicate an easy way to diagnose Parkinson's disease early, even before the onset of symptoms," Munoz said. The diagnosis of Parkinson's disease is very difficult, especially in the early stages. Parkinson's disease is a common degenerative disease of the central nervous system in the elderly. The main symptoms include trembling of the limbs and slowed movement. The current main treatment method is dopamine supplementation, but its effect is gradually diminishing.