Research progress on animal models of novel coronavirus pneumonia

  Coronavirus disease 2019 is an acute infectious pneumonia. The first symptoms of infected patients are mainly fatigue, dry cough, fever, and more serious symptoms such as respiratory distress gradually appear.

  At present, it is not yet fully understood the transmission route of the new coronavirus pneumonia, new research and development, vaccine research and development and treatment methods. Animal models are widely used to study the causes of various human diseases. Currently, there is no suitable animal model that can completely simulate the clinical manifestations of patients with new coronavirus pneumonia to determine the cause. Therefore, it is very important to establish and screen animal models suitable for the study of novel coronavirus pneumonia.

  This article reviews the current research status of the new coronavirus pneumonia animal model, compared the advantages and disadvantages of various animal models in the basic research of the new coronavirus pneumonia, and compared the advantages and disadvantages of the new coronavirus pneumonia animal model. Organize the latest research progress on different types of animals to provide reference for the detailed development of experimental animal models in the post-new crown era.