SARS-CoV-2,冠状病毒,胆固醇-25-羟化酶 z-bo 2020-10-30 449

　　The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant worldwide. Currently, there is no US Food and Drug Administration (FDA) approved method for the treatment of COVID-19. Although several treatments are undergoing clinical trials, current standard treatments include providing patients with convalescent serum and antipyretics. To accelerate the search for new treatments for COVID-19, scientists are testing reusable drugs-these drugs have been approved by the FDA for the treatment of other diseases.

　　Therefore, it is known to be safe to use-reduce the ability of this virus to infect. In a new study, researchers at the University of California San Diego School of Medicine found that cholesterol 25-hydroxylase (cholesterol 25-hydroxylase, CH25H) can remove cholesterol from cell membranes, thereby preventing the coronavirus SARS. Found-CoV-2 enters the host cell. A related study was recently published in EMBO, entitled "Cholesterol 25-hydroxylase inhibits SARS-CoV-2 and other coronaviruses by consuming membrane cholesterol." The corresponding author of this article is the Department of Pediatrics, University of California, San Diego School of Medicine. Dr. Tariq Lana, head of the Department of Genetics.