小鼠模型,阿尔兹海默病 z-bo 2020-11-03 299

　　New research shows that two diseases, Alzheimer's disease and cerebrovascular disease, can aggravate the symptoms of the disease. The two research groups have recently studied this subject at the same time, and verified this conclusion from different aspects through mouse models.

　　Merphy and his team's research synthesized the effects of three types of diabetes, Alzheimer's disease and cerebrovascular disease on mouse models. Wilcock and her team also studied the effects of Alzheimer's disease and hyperhomocysteinemia in mouse models. High levels of homocysteine are associated with many diseases, including cerebrovascular diseases.

　　The studies of the two teams have reached similar conclusions. The primary pathological characteristics of Alzheimer's disease have not changed, but the learning ability and memory of the patient are more significantly reduced. In the study of mouse models, having Alzheimer's disease and cerebrovascular disease at the same time will increase the severity of the disease. Such research results can explain why 40% of Alzheimer's patients also suffer from cerebrovascular disease, and may be helpful in treating the disease in the future.