实验动物,裸小鼠 z-bo 2020-07-28 691

　　1. Species protection requirements

　　Theoretically speaking, protection is to use female and male mice with nu/nu genes as targets for protection and reproduction, but replication in this way will result in low pregnancy and birth rates and low fertility. Go down. Therefore, hairless male mice and hairy female mice (gene nu/+) are usually bred and protected. When preserving seeds, please pay attention to the fertility of the mother, the fertility of the mother, and the choice of a father with a father. Mass breeding of mice, high survival rate, healthy and developed hairless males and female hairy females, need to record the selection of other mice, males and females should be kept separately.. Breeding inbred nude mice requires the same inbred mice.

　　2. Mating age requirement

　　Select 75-90 days old hairless male mice and hairy female mice (genotype nu/+) as spare breeding mice. Before breeding, remove dysplastic mice.

　　3. Copying and manufacturing methods

　　The basic requirements are the same as above. During the production process, hairy lactating mice should be distinguished from males and females within 10 days. Eliminate all unsuitable male lactation period and female offspring, improve the survival rate of nude mice.

　　4. Weaning time

　　The weaning time of young mice is about 21-25 days.

　　5. Feeding management

　　Nude mice are more difficult to feed and manage than ordinary mice. Drinking water, feed, cooking utensils and equipment must be strictly disinfected, and air must meet at least Class 10,000 purification requirements. Please avoid during the breeding process. Direct contact between human skin and nude mice requires a high-quality, delicious and nutritious diet.

　　Other reproduction and management of the same mouse.