动物行为学实验 z-bo 2020-11-12 442

　　Cognition is the process by which the body recognizes and acquires knowledge, including memory, language, visual space, calculation, execution, and understanding judgment. Cognitive dysfunction refers to the pathological process of learning and memory caused by abnormalities in the brain's advanced intelligent processing, accompanied by changes in aphasia and apraxia. With the continuous extension of human life expectancy and the advent of the aging population, the prevalence of neurodegenerative diseases (such as Alzheimer’s disease, Parkinson’s disease, etc.) related to cognitive dysfunction continues to increase, which will give families and socio-economic benefits. Added a heavy burden. Cognitive dysfunction caused by other non-neurological diseases, such as diabetes and hypertension, also seriously affects the quality of life of patients. Studying the pathological mechanism of cognitive dysfunction is of great significance to the prevention and treatment of related diseases.

　　Animal behavior assessment is widely used in many fields of neuroscience, especially in the assessment of animal models of cognitive dysfunction-related diseases, and the study of physiological mechanisms. Impairment of learning and memory is a common manifestation of cognitive dysfunction. Among many behavioral experiments, the most common ones are to evaluate learning and memory function. Among them, working memory and reference memory are often used to evaluate the cognitive function of experimental animals. Working memory includes attention, short-term memory and information processing; reference memory is considered a long-term, permanent memory or habit, which has a larger capacity, longer duration, and stronger anti-interference ability than working memory .