Mouse experiments revealed that low-dose penicillin may induce long-term behavioral changes in offspring

  In a research report published in the international journal Nature Communications, researchers from McMaster University and other institutions completed a landmark study. They found that low-dose penicillin was provided to pregnant mice clinically It may lead to long-term behavioral changes in the offspring of mice; these changes include increased levels of aggression and decreased levels of anxiety, as well as changes in neurochemicals in the brain and an imbalance of intestinal microflora. A certain amount of lactic acid bacteria in mice can help prevent the above changes.

  Researcher Dr. John Bienenstock said that we have found that giving mother mice a low dose of penicillin during the third trimester of pregnancy and early in the birth of offspring will change the body’s behavior and the balance of microbes in the gut. In the body, researchers are increasingly concerned about the long-term effects of antibiotics. Researchers also discovered that a special probiotic can help prevent the harmful effects of penicillin.

  Other studies have shown that large doses of broad-spectrum antibiotics in adult animals can affect their behavior. However, there is no research to detect clinical doses of commonly used narrow-spectrum antibiotics, such as penicillin, on the intestinal and behavioral changes of the body. Impact. Bienenstock said that currently no babies in North America will receive a complete course of antibiotics in their first year of birth; antibiotics are not added in advance, but we can find traces of antibiotics in meat and dairy products. If the mother takes these drugs When the effect of the virus is inherited to the unborn or post-natal baby, this may cause another problem, namely the long-term effect of the consumption of antibiotics on the human body.