动物造模 z-bo 2022-02-03 402

　　The traditional Chinese medicine "syndrome" model is to reproduce the different clinical manifestations of animals and reveal different syndrome types.

　　(1) Yang-deficiency model

　　intramuscular injection of hydrocortisone acetate, oral administration of diazol, hydroxyurea or surgical removal of both adrenal glands.

　　(2) Yin deficiency model

　　Ingestion of thyroid tablets, subcutaneous injection of L-thyroxine sodium salt, artificial high intestinal fistula surgery. (3) Spleen deficiency model

　　'S low-protein diet contains rhubarb, rh powder, senna or subcutaneous injection of reserpine.

　　(4) Cold syndrome model

　　Inject the triple vaccine intraperitoneally, orally for colds and diarrhea.

　　(5) Fever syndrome model

　　Oral or inject warm medicine. In (6)

　　In the experimental model of

　　, highly toxic bacteria are injected into the muscle layer of the dog’s appendix. (7) Congestion model

　　Subcutaneous injection of 10% polymer dextran, rabbit dose 1.5 g/kg; rabbit intravenous injection of 10% dextran salt solution, body weight 5 ml/kg; 0.1 epinephrine subcutaneous injection 0.2 ml / twice a day with water for 5 minutes, and stimulate 1- 2 days. (8) Blood deficiency model

　　"On the first 1, 4, and 7 days of the experiment, 2% acetophenylhydrazine saline was injected subcutaneously. For a 100g body weight, the first time is 1ml, and the second time is the third time, which is 0.5ml. The mice had blood drawn every other day, 7 times in total, and the blood loss accounted for 20% of the total blood volume each time. Thereafter, the blood loss was 0.5 ml each time, and the diet was restricted.

　　(9) Liver depression model

　　Selected rats, with 2 ml of mugwort injection (including 2.0 g of raw materials), intraperitoneal injection once a day after half a month, every other day.. intraperitoneal injection of 0.6ml mugwort leaf injection to mice every day Liquid (contains 0.3g of crude drug). The model was formed about 40 days after injection.