动物造模 z-bo 2022-02-03 403

　　[Modeling mechanism] Rapid atrial pacing is the same as the atrial fibrillation model.

　　[Modeling method]: Choose an adult mixed dog. After anesthesia, monopolar pacing electrodes are inserted through the veins into the right ventricle and right atrium, and connected to the pacemaker, which was previously implanted in the skin below the neck. Radiofrequency ablation can block atrioventricular conduction (to prevent the adverse effects of rapid atrial pacing on ventricular function). The pace of the ventricles is 80 beats/minute, and the pace of the atria is 400 beats/minute. After 7 to 13 days. Perform anesthesia again, tracheal intubation, left chest incision, and open the heart bag to expose the heart, peel the heart from the body, and apply S1S2 stimulation to multiple parts of the atrium. The circumference of S1S1 is in the range of 200-500 milliseconds, and S2 stimulation is given every 15 S1 stimulations to induce atrial tachycardia.

　　[Model Features] The success rate of this model is about 65%. The speed of most rooms automatically ends after stopping the stimulation, and the average room speed lasts for 11 seconds.

　　[Model Evaluation and Application] can be used to study the etiology and treatment of atrial tachycardia.