动物造模 z-bo 2022-02-03 473

　　[Modeling mechanism] The mediastinal nerve is a mixed nerve plexus, including the parasympathetic ganglion, sympathetic nerve and limb afferent nerve. The right mediastinal nerve is mainly located in the abdominal area near the caudal side of the superior vena cava adjacent to the maxillary sinus, and electrical stimulation of the right mediastinal nerve causes the pacemaker to move from the sinus node to the right atrium, resulting in atrial tachycardia. Will cause jitter.

　　[Modeling method]: Choose an adult mixed dog. After anesthesia, the chest cavity is opened and formaldehyde is injected into the atrioventricular junction to prevent the atrioventricular conduction. The ventricle beats at a rate of 60 beats per minute. During the atrial refractory period, the right mediastinal nerve S1S1 is stimulated with an intensity of 1-2 mA, a pulse width of 1 ms and an interval of 5 ms to induce tachycardia.

　　[Characteristics of the model] This model first shows bradycardia and then atrial tachycardia.

　　[Model evaluation and application] can be used to study the role of autonomic nerves in the development of atrial velocity.