治疗脑癌 z-bo 2020-12-17 326

　　Japanese researchers recently announced that a red food coloring has been found to be effective in the treatment of malignant glioma through animal experiments, and it is expected that new therapeutic drugs will be developed on this basis in the future.

　　Glioma is a type of brain tumor. The treatment of malignant glioma is very difficult. It is difficult to completely remove the affected area through surgery. It also needs to be used with drugs. However, the effect of existing drugs is not satisfactory, so it needs to be developed better Drug. Researchers from the Institute of Basic Biology of Japan and other institutions reported in the new issue of the British "Scientific Reports" that because it is known that there is an enzyme called PTPrZ in malignant glioma cells that can exacerbate canceration, they are about 26,000 types. The compound was looking for substances that could inhibit this enzyme, and it was found that a low-molecular compound called SCB4380 was effective. This compound is used as a red pigment in food and cosmetics in Japan.

　　Direct use of this substance cannot pass through the cell membrane of malignant glioma, but researchers have found that using a liposome to encapsulate this pigment can overcome this problem. Researchers conducted experiments on 16 rats with malignant gliomas in their brains. They injected pigments wrapped in liposomes into their brains. They found that the tumors shrank in size after 7 weeks, only the size of the control group without pigment injections. The mouse tumor is about half the volume.

　　Researchers said that they will continue to carry out research on this basis in the future, and strive to develop new drugs that can effectively treat malignant glioma.