大鼠实验模型 z-bo 2021-11-11 360

　　Objective: To establish a new type of SD rat tibial distraction osteogenesis model.

　　Methods: Forty male SD rats were osteotomy of the right tibia and shortened 4 mm. They were fixed with a circular distraction external fixator designed by the self-research. During the fracture repair period, the tibia height was restored by the distraction external fixator. Gross observation, imaging observation and histomorphological methods observe the healing and recovery of the osteotomy site.

　　Result: The external fixator is stable and effective after the operation, and has no obvious effect on the functional activities of the rats. The tibia is recovered in height and bone union.

　　Conclusion: The rat tibia distraction osteogenesis model established in the experiment is reliable, practical, and repeatable.