动物造模,大鼠子宫角瘘管模型 z-bo 2021-01-09 351

　　Objective: To explore the feasibility of rat uterine horn fistula model.

　　Method: After anesthetizing the rat, place the fistula near the uterine horn of the peripheral uterus to study histopathology and fertility.

　　Results: Rat endometrial thickness fistula model group (497.68±81.64) μm indwelling uterine horn, control group (537.90±77.29) μm and fistula model group (503.56±76.34) μm contralateral uterine horn compared with... . The difference in proportion was not significant (P≥0.05); the number of rat embryo transfer fistula model group (9.67±1.95) was significantly reduced (P0.05) compared with the control group (12.15±2.06).

　　Conclusion: The angular fistula catheter model has little effect on the structure of the rat uterus, and can meet the test requirements of long-term injection of pathogenic microorganisms or chemicals into the uterine cavity.