动物造模,长爪沙鼠NAFLD模型 z-bo 2021-12-27 351

　　Aiming at the post-genome era, Garville also needs to use new technologies for in-depth research to achieve sustainable development. The animal models currently in use are more or less flawed. The search process is very similar to that of human diseases, the method is simple and easy to implement, the model formation rate is high, the genetic structure of the combustion system can be determined, and the combustion system can be selected. .. Marking is our main purpose.

　　 In this study, we made a simple feed ourselves, and for the first time established an induced NAFLD model through rapid modeling. After long-term observation of closed populations, we discovered the natural aging model for the first time and tested it using commonly used clinical serum electrophoresis detection techniques. The PCR-DGGE technology has been established for input and evaluation and evaluation of model gut microbes. Then, using transcriptome sequencing technology, we conducted a detailed sequence analysis of the induced gerbil model and the spontaneous gerbil model, and it is of great significance for some highly expressed genes in Garville's rapid and spontaneous modeling. Different ways; third, Gerville hyperlipidemia, which starts from genes closely related to classical theory and predicts the ability to evaluate genes using candidate gene methods and immunohistochemical methods. Correlation; Finally, a large sample was drawn from the ZCLA closed group, covering two microbial production groups to assess the genetic diversity of the selected gene SNP and confirm that it was inherited as NAFLD. Mark the possibility of selecting inbred lines.