动物造模,慢性心肌缺血小型猪模型 z-bo 2021-01-12 636

　　Purpose: Place a humanoid contraction ring on the left anterior descending branch through surgery to explore the feasibility of continuous needle implantation for the treatment of chronic myocardial ischemia in miniature pigs?

　　 Method: To establish a chronic myocardial ischemia model in minipigs, place a humanoid contraction ring in the left anterior descending branch of the left anterior coronary artery in Bama minipigs, and randomly compare with the treatment group (puncture at the "Neiguan" point). It is divided into several groups (puncture at the "Zu Sanli" point) and embedding at the "Neiguan" and "Zu Sanli" points. Do you want to collect materials after 6 weeks of electroacupuncture?

　　Result: Postoperative gross pathology showed that there are ischemic areas in both groups. Mitochondrial vacuolar fibrosis in both groups?

　　 Conclusion: Acupuncture at the "Neiguan" point of the pericardial meridian can protect the myocardium by reducing myocardial ischemia, but can it inhibit the existing myocardial ischemic damage? Does it indicate that it is possible to place a humanoid contraction ring in the left anterior descending coronary artery to establish a large experimental animal model of chronic myocardial ischemia in pigs and use needle transplantation for treatment?