z-bio 2021-01-14 505

　　Objective: To explore a systematic assessment method for the model of blood stasis syndrome in rats with precocious puberty.

　　 Method: By observing the precocious bloody moist stagnation group? Precocious adolescents are not in the stagnant group? Blank control group and parent model group? Did the symptom performance of female SD rats in the control group and the open-field experimental data of their parents combine with animal models to explore the systematic evaluation of diseases and syndromes? Results: Compared with the maternal control group, there was no significant difference in the weight gain of female rats in the maternal model group (P\→0.05), while in four-week-old female rats, there was no significant difference in precocious puberty and hemorrhoids. Is the weight of female rats significantly lower than the blank group (P0.05)?

　　 Conclusion: High-fat diet did not increase the weight of female SD rats. This indicator may not be an important indicator for the systematic evaluation of animal models of stagnant blood loss syndrome. The behavioral changes of rat model of stagnant bleeding syndrome are similar to the clinical manifestations of the syndrome, and field experiments can be used to further study stagnant sputum syndrome. In the animal model evaluation method, there was no difference in the behavior of female puppies in each group.