动物造模,Wistar大鼠全厚植皮模型 z-bio 2021-01-19 328

　　Objective: To establish a model of full-thickness skin transplantation in Wistar rats and introduce experimental methods to improve the success rate of skin transplantation in Wistar rats.

　　Method: Wistar rats of 12th grade, male, 3 months old, weighing 300-330g, body weight and anesthesia, skin preparation and labeling, rat fixation and disinfection, full-thickness skin section cutting and trimming, whole skin thickness for replanting The experimental procedure to take steps to avoid bites and scratches in rats is to establish a full-thickness skin graft model.

　　Result: All 12 Wistar rats in this group survived on the chest on the skin, and there was no skin infection and necrosis. After the operation, the rats can eat normally and move around freely. No rats died abnormally after feeding for 1-2 months.

　　Conclusion: The experimental method established in this experiment is simple and effective, and provides specific experimental methods for related research.