动物造模,小鼠造血系统 z-bio 2021-11-06 293

　　Objective: To study the changes of hematopoietic system in mice after long-term intake of Polygonum multiflorum.

　　 Method: The mice were randomly divided into two groups. The control group was fed with a normal diet. After 10 months, the mice were sacrificed to the Polygonum multiflorum diet group fed with the multiflorum multiflorum diet, and the peripheral blood and spleen were analyzed. Flow cytometry, various cells in the thymus and bone marrow.

　　Result: In the F. multiflorum feed group mice, spleen B cells increased, thymus CD4 + cells increased, and CD8 + cells decreased. Bone marrow hematopoietic stem cells are significantly reduced, in which quiescent cells increase, and proliferation and dividing cells decrease.

　　 Conclusion: Long-term appropriate intake of Polygonum multiflorum can help delay the aging of the hematopoietic system in mice and maintain the stability of the hematopoietic system.