动物造模,急性心肌梗死 z-bio 2021-12-04 263

　　Purpose: Do you apply myocardial contrast echocardiographic visual assessment to rabbit acute myocardial infarction models to evaluate the blood perfusion of the infarcted area after acute myocardial infarction?

　　Method: A group of 20 clean Japanese big-eared rabbits were randomly selected to establish an acute myocardial infarction model group (group A) and a sham operation control group (group S), respectively. The values were 10 ?, about 45 minutes after collection, 20 minutes to 2 hours to 6 Comprehensive evaluation and analysis of conventional ultrasound and echocardiographic surgery in hours. What is the blood perfusion of the model segment after acute myocardial infarction in rabbits? After the experiment, is the myocardial tissue of the model segment removed for pathological examination?

　　Results: The conventional echocardiogram showed the range of motion of the model segment, which changed significantly at different time points after the Japanese rabbit ischemia, and the myocardial histopathology changed significantly. At the same time, the myocardial contrast echocardiogram was visualized. The evaluation showed that the acute myocardial infarction model was successfully established; at the same time, the myocardial blood volume and perfusion rate of the model segment of the A group were not infarcted, which was significantly lower than this segment. The corresponding segment of the S group was compared with conventional echocardiography and histopathology. The result of the inspection?

　　Conclusion: The visual assessment of myocardial contrast echocardiography can make accurate decisions. The blood perfusion status of the infarcted myocardial segment after acute myocardial infarction.