动物造模 z-bio 2021-02-04 438

　　Purpose: Have you observed the effects of micro-arc oxidation and alkali treatment on the surface properties, biocompatibility and osteogenic potential of porous tantalum?

　　Method: After micro-arc oxidation and alkali treatment on the porous tantalum sheet, observe the quantity with a scanning electron microscope. Changes in surface micropores? Surface calcium and phosphorus deposition and contact angle? Tantalum sheet transplantation to repair the rabbit skull defect model, do you observe bone healing at 4 and 12 weeks?

　　Result: The scanning electron microscope has more micropores and calcium, and the contact angle of phosphorus deposited on the surface of the treatment group is very small (P\u003c0.05)? After transplanting the porous tantalum sheet, did all the animals grow well and the wound healed well? The CT observation of the porous tantalum sheet and the surrounding bone tissue showed a good combination; the calcaneal labeling test showed that there was new bone growth in the porous tantalum material at the 12th week; scanning electron microscope observation showed that the hollow tantalum material had new blood vessels and Does trabecular bone grow in the material within 4 weeks of 12 weeks?

　　 Conclusion: Micro-arc oxidation and alkali treatment can change the surface shape of the porous tantalum surface treatment material. Does the porous tantalum sheet have excellent biocompatibility and osteogenic ability?