动物造模,慢性心肌缺血小型猪模型 z-bio 2021-10-26 335

　　Objective: To explore the feasibility of a series of methods for the treatment of piglet chronic myocardial ischemia model. In the model, the mastoid stenosis ring is surgically placed in the left anterior descending artery of the needle?

　　Method: A model of chronic myocardial ischemia in piglets with the left anterior descending branch of Bama caterpillars was established. The model was placed with a humanoid narrow ring and placed in the treatment group ("Neiguan" puncture") and the control group ( "Zu Sanli"). Randomly divided into puncture). Point) and implant needles at "Neiguan" and "Zu Sanli" points respectively, combined with electroacupuncture, will materials be collected after six weeks?

　　Result: Postoperative gross pathology showed that there are ischemic areas in both groups. The "Zusanli" point is larger than the "Neiguan point", indicating the upper structure of the cardiomyocytes. Are there mitochondrial vacuoles in both groups? Fibrosis?

　　Conclusion: Puncture at the "neiguan" of the pericardial meridian can protect the myocardium by reducing myocardial ischemia. Can it inhibit the existing myocardial ischemic injury? This indicates that a humanoid contraction ring can be placed in the anterior descending branch of the left coronary artery and treated with needle implantation to establish a large experimental animal model of chronic myocardial ischemia in pigs.