【Animal Modeling】-Research on the relationship between tree shrew gallstone model and digestive tract substance P

  Purpose: How to study the relationship between the gallstone model formed by feeding tree sh with a high-cholesterol diet and substance P (SP)?

  Method: Detect the expression of SP immunohistochemistry in the gastrointestinal tract by establishing a gallstone model of tree sh. Comparative analysis of the control group?

  Result: Compared with the control group, the expression level of SP immunohistochemistry in the gastrointestinal tract of tree sh was lower than that of the control group (P\u003c0.05), and the tree gall gallstone model was negatively correlated with the normal control group.

  Conclusion: Does Treeshrew gallstones participate in the regulation mechanism of gastrointestinal hormone secretion?