【Animal Modeling】-Mice model verifies that Alzheimer's disease coexisting with cerebrovascular disease can aggravate disease symptoms

  A new study shows that two diseases, Alzheimer's disease and cerebrovascular accident, exacerbate the symptoms of the disease. The two research groups recently studied the subject at the same time and verified this conclusion from various aspects through mouse models.

  A study by Murphy and his team synthesized the effects of type 2 diabetes, Alzheimer's disease and cerebrovascular accident on mouse models. Wilcock and her team also studied the role of Alzheimer's disease and hyperhomocysteinemia in mouse models. Homocysteine levels are associated with many diseases, including cerebrovascular accidents. The research of the two groups reached similar conclusions, the key pathological features of Alzheimer's disease have not changed, but the learning ability and memory of the patient are even greatly reduced.

  In mouse model studies, the simultaneous development of Alzheimer's disease and cerebrovascular disease increased the severity of the disease. The results of these studies can explain why 40% of Alzheimer's patients also suffer from cerebrovascular disease, and may help treat future diseases.