【Animal Modeling】-Monkey HIV enters the body within a few days to fight drugs

  The latest research shows that monkey HIV can escape the attack of anti-AIDS drugs within a few days after entering the human body. This discovery has had a major impact on AIDS treatment research. According to the latest research report, if humans are also infected with HIV, they must be treated "early".

  Not long ago, the medical community announced that an American girl Mississippi Baby (Mississippi Baby) started taking retroviral drugs 30 hours after her birth. She was initially "cured" after 18 months of continuous treatment and was discovered in July this year. She suffers from AIDS. The virus has been resurrected.

  reported that an important challenge in curing AIDS is that HIV has a hiding place, that is, infected immune cells. HIV DNA can exist in the infected immune cells for many years, which can avoid the interference of antiretroviral drugs and the immune system.

  For most patients, once you stop taking the drug, the virus will start to replicate. In other words, the patient must take herbal medicine for life. When these hidden cells invade the human body, when and how HIV discovers these hidden cells is still unknown. A new study found that rhesus monkeys infected with simian immunodeficiency virus (simianHIV) have an "unexpected early" appearance, and these cells hide them in the body after infection. These monkeys received treatment on the 3rd, 7th, 10th, and 14th days after infection, but as long as the drug treatment was stopped, the virus began to replicate, but the monkeys who had been treated previously had replicated the virus, and it was too late.