动物造模,遗传性耳聋,基因编辑 z-bio 2021-10-26 499

　　According to the "Guardian" report, after researchers used a technique to "cut out" the genetic mutation that causes progressive deafness, the "Guardian" reported: "A breakthrough in gene editing functions to prevent hereditary hearing loss. "

　　Although many people believe that hearing loss is mainly related to aging, in fact many conditions are hereditary.

　　It is estimated that there are more than 400 forms of hereditary hearing loss, many of which are progressive (they get worse over time).

　　The mice in this study reproduced with a genetic mutation in the TMC1 gene, which caused the death of the fine hair cells in the inner ear and stopped growing. As the hair cells die, hearing will gradually deteriorate.

　　Then, the scientists banned genetic mutations by injecting a mixture of a protein and a genetic material called RNA into the ears of newborn mice.

　　They found that mice that had been treated to disable the gene mutation had healthy inner ear hair cells and had better hearing than untreated mice.

　　This is an interesting news-there is currently no solution to the root cause of hereditary hearing loss.

　　But the standard warning applies: What works in mice may not work in humans.