动物造模,荷子宫肌瘤组织移植瘤 z-bio 2021-11-23 309

　　Objective: To establish a rat model of uterine fibroids with tissue inhibitor transplantation immunosuppression, and to provide a new animal model for the study of uterine fibroids.

　　Method: Mycophenolate mofetil (MMF), a forced-fed immunosuppressant, was administered to rats 2 weeks before surgery until the end of the experiment? According to the different hormones supplemented after peritoneal transplantation, 20 Wistar rats were randomly divided into four groups. Did you take samples 4 weeks after the operation to observe the morphology and tissue morphology of group A (fenmax), group B (estradiol), group C (Duffton), group D (control group), uterine fibroids?

　　Result: The modelling success rate of group A is 90%, the modelling success rate of group B is 40%, and the modelling success rate of group C is 0?

　　Conclusion: The success rate of rat uterine fibroids transplantation tumor model is high, and the cost is low.