动物造模,荷子宫肌瘤组织移植瘤 z-bio 2022-01-14 336

　　Objective: To establish a model of immunosuppressive rat uterine fibroids by tissue inhibitor transplantation, and provide a new animal model for the study of uterine fibroids.

　　Method: Forced feeding mycophenolate mofetil (MMF) immunosuppressant until the end of the experiment on rats 2 weeks before the operation? According to the different hormones supplemented after peritoneal transplantation, 20 Wistar rats were randomly divided into four groups. Did you take samples 4 weeks after the operation to observe the morphology and tissue morphology of group A (fenmax), group B (estradiol), group C (Duffton), group D (control group), uterine fibroids?

　　Result: The modelling success rate of group A is 90%, the modelling success rate of group B is 40%, and the modelling success rate of group C is 0?

　　Conclusion: The success rate of rat uterine fibroids transplantation tumor model is high, and the cost is low. Study on new animal models of transplanted uterine fibroids?