Postpartum depression (PPD) refers to a series of depressive symptoms in which the child appears from the beginning of delivery to the postpartum, such as sadness, depression, crying, irritability, irritability, and lack of confidence in life. Suicide and infant murder are prone to occur. The incidence of PPD is related to psychosocial and biological factors, and the incidence is about 10% to 15%. Relevant studies have shown that the proportion of women who have symptoms of anxiety or depression within a few weeks, months or years after delivery is significantly higher than in other periods; one in ten women have symptoms of anxiety or depression after delivery. One month after delivery. The incidence is the highest. Compared with simple depression, due to the complexity of the disease and the special period after delivery, PPD differs from animal models in behavior evaluation. This article outlines animal models of postpartum depression and how to evaluate their behavior.