动物造模,直肠癌肝转移,异种移植 z-bio 2021-09-23 442

　　The liver is the main target organ for colorectal cancer metastasis, and the liver metastasis of colorectal cancer is also the main cause of death in patients with colorectal cancer. In recent years, studies have shown that primary tumor tissue xenotransplantation for liver metastasis of colorectal cancer. (Patient-derived tumor xenografts, PDTX) animal models can better reproduce the characteristics of clinical tumor patients. The modeling methods are mainly divided into orthotopic heterotopic transplantation and heterotopic heterotopic transplantation models. This article reviews the methodology and scope of PDTX animal modeling. The purpose of the colorectal cancer liver metastasis model is to provide a reference for experimental modeling?