Why build an animal model of depression? -Animal modeling

  Although the incidence of depression has increased in recent years, there are still many unclear points about the pathophysiological mechanism of depression. Animal models of depression can mimic the clinical symptoms of human depression, and effective drugs can be used to correct these symptoms. It has important application value in the pathogenesis of depression, the development of antidepressants and the evaluation of clinical efficacy. Nowadays, common animal models of depression are mainly established through stress, surgery, drugs and genetic modification of children.