【Animal Modeling】-How to build an ADHD experimental animal model?

  Objective: To summarize the research status of ADHD animal models, analyze the advantages and disadvantages of various models, provide references for establishing ideal ADHD animal models, and provide new ideas for future ADHD experimental research.

  Method: Collect literature related to ADHD animal models, analyze and summarize the source and application scope of various models, and summarize their advantages and disadvantages.

  Results: ADHD models are divided into four main types: genetic models, nerve injury models, artificial screening models and environmental adaptation models. These four models have different modeling goals and different application ranges, and each has its advantages and disadvantages.

  Conclusion: According to relevant standards, there is no ideal ADHD animal model. SHR rat is currently a relatively complete model. It is an important research direction to screen animal models according to research purposes, and to establish an ideal ADHD animal model.