Nasopharyngeal carcinoma is one of the most common head and neck malignancies in my country, with a very high incidence, especially in the southeast coastal areas such as Guangdong, Guangdong, and Hong Kong, because the place is relatively hidden. , Mainly found in the middle and late stages. Is early detection and treatment a difficult problem for clinicians? Laboratory animals provide a good model for studying the etiology and treatment of nasopharyngeal carcinoma. The research progress of classic and modern animal models of nasopharyngeal carcinoma lays the foundation for the research and clinical changes of nasopharyngeal carcinoma.