动物造模,强直性脊柱炎 z-bio 2021-06-01 1103

　　Ankylosing spondylitis is a chronic inflammatory rheumatism that mainly affects the axial skeleton and is closely related to human leukocyte antigen B27. Since most patients are very young, spinal stiffness and joint deformities caused by ankylosing spondylitis are socioeconomically harmful. Significant effect? What is the cause of ankylosing spondylitis in experimental animal models? An important vehicle for studying pathological mechanisms and intervention? This article reviews the research progress of spontaneous, inducible and genetically engineered animal models. Basic research on inflammation of ankylosing spondylitis? Provide reference materials and reference materials for new drug development and clinical treatment?