【Animal Modeling】-How to build an animal model of intervertebral disc degeneration?

  Intervertebral disc degeneration is the main cause of low back pain and has a serious impact on people's lives and work. Although the specific etiology is still unclear, research on related animal models has made great progress in recent years. In this article, have you reviewed and discussed the advantages and disadvantages of these methods, as well as their application directions, to lay the theoretical foundation for follow-up research?