【Animal Modeling】-Why establish a 6Hz corneal ignited epilepsy animal model?

  Drug-resistant epilepsy is a major problem in clinical epilepsy prevention and treatment? Animal models of epilepsy are a powerful tool for studying the causes of epilepsy, screening anti-epileptic drugs, and studying the mechanism of drug action. The 0.6Hz corneal kindle epilepsy model is a good animal model of drug-resistant epilepsy. It is recommended by the US NIH as a screening tool for the evaluation of new drugs for drug-resistant epilepsy. However, the 6Hz kindle animal model of epilepsy is domestic and there is no systematic report abroad. . Review the development history, manufacturing methods and symptoms of the model, review its etiology and application, and provide powerful tools and standard models for elucidating the pathophysiology of drug-resistant epilepsy and drug screening for drug-resistant epilepsy.