Traditional Chinese herbal medicine has great advantages in the prevention and treatment of oxaliplatin-induced neuropathic pain (chemotherapy-induced perineuropathy, CIPN), but its application and specific mechanism of action still need to be studied and discussed in depth. Animal models that are more accurate and more in line with the development and development of clinical diseases are used as research media.
This article discusses in detail the establishment and standards of acute models and chronic CIPNs caused by oxaliplatin in recent years, as well as their application in Chinese medicine, related evaluations and explanations, and future research. I hope you can have a reference.