动物造模,抽动障碍动物模型 z-bio 2021-06-03 538

　　Tic disorder is a neurodevelopmental disorder that is more common in childhood. It is mainly manifested as involuntary repetitive movements, sudden movements and vocalizations, accompanied by attention deficit hyperactivity disorder, learning disabilities, obsessive-compulsive disorder, conduct disorder and so on. It will have a serious impact on children's learning, social adaptability and mental health development. However, its etiology, pathogenesis and pharmacological mechanisms have not yet been fully elucidated, and these basic studies need to be further studied and verified through animal models.

　　At present, there are many ways to establish tic disorder models, mainly based on the possible causes of the disease, such as neurotransmitter abnormalities, immune disorders, genetic factors, etc., but there is no working animal model at all. Meet the requirements of tic disorder.

　　This article is a summary of commonly used animal models of tic disorder, which provides a reference for experimental research.