【Animal Modeling】-How to establish an animal model of lung cancer bone metastasis?

  Bone metastasis is one of the common complications of lung cancer. The higher the patient's survival rate, the greater the risk of bone metastasis. The animal model of lung cancer bone metastasis is an important tool for the study of lung cancer bone metastasis. It is very important for the interpretation of the pathophysiological mechanism of lung cancer bone metastasis and the development and evaluation of lung cancer treatment methods.

  This article will review the research status of lung cancer bone metastasis animal models reported at home and abroad, and explain in detail lung cancer cell lines, experimental animal strains, model construction methods, evaluation methods and other important references for lung cancer research.