动物造模,克罗恩病,动物模型 z-bio 2021-06-16 759

　　Crohn's disease is a chronic inflammatory bowel disease, and its etiology has always been a hot and difficult point in medical research. Choose an animal model suitable for studying this disease, explore potential therapeutic targets, and develop new therapies. Medicine is especially important.

　　With the development of molecular biotechnology, animal models that can be used to study Crohn’s disease are becoming more and more diverse. From early chemically induced animal models to later spontaneous and cell transplant animal models, they are now widely used. Researchers have increasingly suitable options, such as genetically engineered animal models.

　　This article mainly summarizes the pathogenesis, advantages and disadvantages of these animal models, and provides reference materials for basic research.