Diabetes is a metabolic disease characterized by high blood sugar caused by a variety of factors, posing a serious threat to human health. The establishment of corresponding animal models of diabetes is essential for the study of its etiology, prevention, diagnosis and screening of new therapeutic drugs.
Based on the overview of constructing spontaneous and induced type 2 diabetes animal models, this article focuses on how to use genetic engineering technology to construct type 2 diabetes animal models, as well as the advantages and disadvantages of various construction methods. Provide a suitable animal model for the pathogenesis and treatment of diabetes.