Campylobacter jejuni mainly causes food-borne gastrointestinal diseases and has an important impact on human health. However, the establishment of related mouse infection models is a challenge in the study of this pathogen.
This article outlines the key factors affecting the establishment of a Campylobacter jejuni infection model. This includes strain pathogenic factors, mouse strain, immune function, intestinal flora, diet composition, host adaptation and other factors. It provides a reference for the successful establishment of a suitable mouse infection model.