动物造模,先天性白内障小鼠 z-bio 2021-06-21 282

　　Objective: To establish background data on the body weight, main organ weight, and blood physiological and biochemical indexes of SPF-class congenital cataract mice.

　　Method: Normal KM mice aged 28 and 56 days were used as the control group, and congenital cataract mice of the same age were used as the experimental group. Measure the mouse body weight, body weight, main organs and blood and other physiological and biochemical indicators.

　　Result: Compared with 28-day-old KM mice, not all indicators of cataract mice of the same age are statistically significant. Compared with 56-day-old KM mice: (1) The weight of male spleen mice, the weight of heart, liver and lung, kidney and testis are all significantly different (Pu003c0.05 or P). u003c0.01). (2) The blood test data showed that the average platelet volume, platelet distribution width of female rats, and the ratio of white blood cells, platelets, and lymphocytes of male rats were statistically significant (Pu003c0.01). (3) The blood biochemical test data showed that there were statistically significant differences in alkaline phosphatase, uric acid, glucose, total protein, alanine aminotransferase, albumin, urea and triglycerides in male mice (Pu003c0).05 or Pu003c0. 01).

　　Conclusion: Compared with 56-day-old cataract and KM mice, there are certain differences in body weight, major organ weight, and some physiological and biochemical indicators. The research results can provide reference data for scientific researchers.