动物造模,猕猴脊髓损伤 z-bio 2021-06-23 469

　　Purpose: To provide a simple and feasible anesthesia plan for the construction of a spinal cord injury model in rhesus monkeys and the success of other long-term operations in rhesus monkeys.

　　Method: 10 male adult rhesus monkeys were selected, and a combined anesthesia method of intravenous propofol and isoflurane inhalation was used to maintain anesthesia. Record anesthesia induction time, anesthesia maintenance time and anesthesia recovery time. Continuous monitoring and analysis of blood oxygen saturation (SpO2), respiratory rate (RR) and heart rate (HR) to evaluate the feasibility and effectiveness of the anesthesia plan.

　　Result: All 10 macaques completed the experiment according to the experimental design. The induction time of anesthesia is short, the effect is quick, the important signs are stable during the anesthesia, and the effects of sedation, analgesia, and muscle relaxation are satisfactory. The postoperative recovery was rapid and complete without complications from anesthesia.

　　Conclusion: Propofol and isoflurane anesthesia is a safe and effective long-term anesthesia program for rhesus monkeys.