Does the number of chemicals available to humans continue to increase with the development of society, leading to a decline in reproductive function? Are the problems of decline in reproductive function becoming more and more serious, and is the research on reproductive toxicity becoming more and more important? Very important Compared with rodents, the reproductive system of non-rodents is closer to humans, and the results of experiments are more informative. This article describes the characteristics of non-rodents and their current reproductive toxicity. Do you want to summarize the application status of your research in order to expand the choice of animal models in your experiments and provide new research methods for preclinical safety assessment of research materials?